Lopid (also known as a fibrate) combined with diet is used to help reduce fat (triglycerides) and cholesterol in the blood. This drug is usually prescribed after drug treatments that have not been completely successful and is aimed at lowering cholesterol (e.g. diet change, increase in exercise, weight loss if overweight). This drug is believed to work by reducing the amount of fat produced by the liver. Reducing cholesterol and triglycerides lowers the risk of heart disease and helps prevent strokes and heart attacks. The drug also helps prevent diseases of the pancreas (pancreatitis) in patients with very high blood levels of triglycerides.
Mode of application
Take the medicine twice a day 30 minutes before meals or as directed by your doctor. Dosage is based on your medical condition and response to therapy. Use this medication regularly in order to get the most benefit from it. It is recommended to take it at the same time each day. The full effect of the drug may produce impact within 1-3 months after the beginning of its administration. It is important to continue taking the medication even if you feel well. Most people with high levels of triglycerides and cholesterol do not feel sick.
The mechanism of action
Lopid is a lipid and cholesterol derivative. It lowers triglycerides and raises the level of cholesterol transported in high-density lipoprotein (HDL) cholesterol in the blood. HDL cholesterol is sometimes called "good" cholesterol because higher concentrations of HDL cholesterol are associated with reduced risk of heart disease. Reduction of triglycerides is partly due to the reduced release of triglycerides from adipose tissue in the body. One large study has shown that Lopid reduces the risk of heart attacks but does not affect the overall life expectancy of people with high cholesterol.
Take the missed dose as soon as you remember. If this occurred while taking your next dose, skip the missed dose. Do not take 2 doses in a row.
Lopid is to be stored at room temperature and in a dry and warm place.
Before taking Lopid, tell your doctor if you are allergic to this medication or have any other allergies. Before using the medication, consult the doctor if you have: liver disease (e.g. primary biliary cirrhosis), gallbladder disease or severe kidney disease. Before using the medication, tell your doctor of your medical history, especially of: diabetes, thyroid disorders (hypothyroidism) and alcohol. Rarely developed serious muscle damage (see Side Effects) can often lead to serious kidney problems.
This medicine may increase your risk of developing kidney problems. Before the end of the medication, tell the doctor if you have any of the following conditions: pending surgery, trauma, severe illness (e.g. sepsis, severe metabolic/endocrine / electrolyte disorders), very low blood pressure or uncontrolled cramps. The drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. We do not recommend drinking alcohol while taking the drug.
The medication should be used only when absolutely necessary. If you are pregnant, discuss the risks and benefits with your doctor. It is not known whether the drug gets into breast milk. Breast-feeding is not recommended while using this drug. Consult your doctor before breast-feed.